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Cord Blood Transplant




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If you, or a loved one is in need of a bone marrow or cord blood transplant, but immediate family cannot provide a good match, doctors have the option of searching the National Marrow Donor Program (NMDP) registry for an allogeneic transplant (donation outside family)

Patients needing bone marrow or cord blood transplants often turn to family members in hopes of a perfect match. However, 70-75% of them fail to find a suitable match within their own gene pool.

It may take months for the medical team to find a donor with a matching blood composition. With the patients cord blood available, the treatment is not delayed beyond a few days. In case the patients cord blood is not available, public cord blood banks have a vast resource of stem cells, which were donated by new parents. The cord blood banking system is highly computerized and one can search for the matching composition very quickly.

Great promise has been shown in the treatment of Krabbe Disease and other rare lysomal storage diseases through the transplantation of cord blood stem cells. Krabbe disease occurs in infants, and if left untreated is usually fatal within 2 years. Researchers from Duke University and the University of North Carolina at Chapel Hill have made ground breaking progress in the treatment of this disease. Their research shows that newborns who receive umbilical cord blood stem cell transplants while they are still asymptomatic have a much higher chance of survival than children who have already shown symptoms. The key is to catch the disease early enough to prevent the loss of critical brain function.

Umbilical cord blood stem cell transplant has been proven to treat Lymphoproliferative disease. This illness is a rare condition that affects the immune system and makes the patient unable to fight off common germs. Brothers Blayke and Garrett of Los Angeles, California were born with this life threatening disease. Thanks to a cord blood transplant, both boys are now living normal, healthy lives.

It is important to understand that some types of blood are more common than others, so finding the right match may take some time. Doctors and NMDP will work together to locate possible matches across the globe, but understanding that protein markers are inherited, some matches may be more difficult to locate than others.

Understanding the cord blood transplant process, the factors involved, and the immediate need of the patient are all important for the patient and their family. However, a family can rest assured that doctors, and those at the NMDP are fervently seeking the best possible matches, so that care of the patient can be focused on during this process.

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